Epidemiology

Leader of this group:

Prof. MD PhD Dag Moster

Photographer:

Ingvild Festervoll Melien

Epidemiology is the formal study of health event patterns in a population, their causes and means of prevention. Epidemiology provides the scientific basis for evidence-based medicine and strategies to improve public health. (Segen's Medical Dictionary)

Norway is in a unique position of undertaking population-based studies due to the large amount of information available in compulsory national registries. The linkage of national databases may generated new knowledge on causes and on long term consequences of different medical conditions. Few other countries worldwide have the possibility to do this sort of studies.

The epidemiology group uses information available in Norwegian national databases to study causes and consequences of perinatal and childhood medical conditions.

Research projects

The impact of conditions related to pregnancy, birth and the newborn period on neurodevelopmental disabilities

Ny kunnskap ervervet gjennom registerbasert forskning på dette området vil kunne ha stor klinisk betydning gjennom bedre å identifisere risikofaktorer i perinatalperioden for senere nevrologiske utviklingsforstyrrelser.

Long term follow up studies of newborns in Norway

Formål med studien: Få kunnskap om hvilke faktorer rundt svangerskap, fødsel og nyfødtperiode som gir økt risiko for senskader for å kunne sette inn målrettete tiltak mot disse.

MOBAND

Studien skal beskrive forekomst, sykdomsforløp, konsekvenser og dødelighet hos barn med cerebral parese (CP) og identifisere mulige årsaker og risikofaktorer.

Collaborative projects

En oversikt over flere forskningsprosjekt.

Publications

Wilcox AJ, Cortese M, McConnaughey DR, Moster D, Basso O. The limits of small-for-gestational-age as a high-risk category. Eur J Epidemiol. 2021 Oct;36(10):985-991.

Linde LE, Ebbing C, Moster D, Kessler J, Baghestan E, Gissler M, Rasmussen S. Recurrence of postpartum hemorrhage in relatives: A population-based cohort study. Acta Obstet Gynecol Scand. 2021 Dec;100(12):2278-2284.

Haug AC, Markestad T, Tjora E, Moster D. Tongue-tie in neonates. Tidsskr Nor Laegeforen. 2021 Aug 12;141.

Cortese M, Moster D, Wilcox AJ. Term Birth Weight and Neurodevelopmental Outcomes. Epidemiology. 2021 Jul 1;32(4):583-590.

Mannseth J, Berentsen GD, Skaug HJ, Lie RT, Moster D. Variation in use of Caesarean section in Norway: An application of spatio-temporal Gaussian random fields. Scand J Public Health. 2021 Dec;49(8):891-898.

Strøm MS, Tollånes MC, Wilcox AJ, Lie RT, Forthun I, Moster D. Maternal Chronic Conditions and Risk of Cerebral Palsy in Offspring: A National Cohort Study. Pediatrics. 2021 Mar;147(3):E20201137.

Vik ES, Aasheim V, Nilsen RM, Small R, Moster D, Schytt E. Paternal country of origin and adverse neonatal outcomes in births to foreign-born women in Norway: A population-based cohort study. PLoS Med. 2020 Nov 4;17(11):e1003395.

Vik ES, Nilsen RM, Aasheim V, Small R, Moster D, Schytt E. Country of first birth and neonatal outcomes in migrant and Norwegian-born parous women in Norway: a population-based study BMC Health Serv Res. 2020 Jun 15;20(1):540.

Forthun I, Lie RT, Strandberg-Larsen K, Solheim MH, Moster D, Wilcox AJ, Mortensen LH, Tollånes MC. Parental Education and the Risk of Cerebral Palsy for Children: An Evaluation of Causality. Dev Med Child Neurol. 2020 Apr 27. Online ahead of print.

Sun BZ, Moster D, Harmon QE, Wilcox AJ. Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring. JAMA Psychiatry. 2020 Aug 1;77(8):823-829.

Ebbing C, Kessler J, Moster D, Rasmussen S. Isolated single umbilical artery and the risk of adverse perinatal outcome and third stage of labor complications: A population-based study. Acta Obstet Gynecol Scand. 2020 Mar;99(3):374-380.

Ebbing C, Kessler J, Moster D, Rasmussen S. Single umbilical artery and risk of congenital malformations: a population-based study in Norway. Ultrasound Obstet Gynecol. 2020 Apr;55(4):510-515.

Vik ES, Aasheim V, Schytt E, Small R, Moster D, Nilsen RM. Stillbirth in relation to maternal country of birth and other migration related factors: a population-based study in Norway. BMC Pregnancy Childbirth. 2019 Jan 5;19(1):5.

Nilsen RM, Vik ES, Rasmussen SA, Small R, Moster D, Schytt E, Aasheim V. Preeclampsia by maternal reasons for immigration: a population-based study. BMC Pregnancy Childbirth. 2018 Oct 26;18(1):423.

Forthun I, Strandberg-Larsen K, Wilcox AJ, Moster D, Petersen TG, Vik T, Lie RT, Uldall P, Tollånes MC. Parental socioeconomic status and risk of cerebral palsy in the child: evidence from two Nordic population-based cohorts. Int J Epidemiol. 2018 Aug 1;47(4):1298-1306.

Riise ØR, Laake I, Vestrheim D, Winje BA, Moster D, Storsæter J. Preterm Children Have Higher Risk Than Full-Term Children of Invasive Pneumococcal Disease During the First Two Years of Life. Pediatr Infect Dis J. 2018 Jul;37(7):e195-e200.

Lie RT, Moster D, Strand P, Wilcox AJ. Prenatal exposure to Chernobyl fallout in Norway: neurological and developmental outcomes in a 25-year follow-up. Eur J Epidemiol. 2017 Dec;32(12):1065-1073. Epub 2018 Jan 8.

Bjellmo S, Andersen GL, Martinussen MP, Romundstad PR, Hjelle S, Moster D, Vik T. Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway. BMJ Open. 2017 May 4;7(4):e014979.

Riise ØR, Laake I, Vestrheim D, Flem E, Moster D, Riise Bergsaker MA, Storsæter J. Risk of Pertussis in Relation to Degree of Prematurity in Children Less Than 2 Years of Age. Pediatr Infect Dis J. 2017 May;36(5):e151-e156.

Stensvold HJ, Klingenberg C, Stoen R, Moster D, Braekke K, Guthe HJ, Astrup H, Rettedal S, Gronn M, Ronnestad AE; Norwegian Neonatal Network. Neonatal Morbidity and 1-Year Survival of Extremely Preterm Infants. Pediatrics. 2017 Mar;139(3). pii: e20161821.

Risnes KR, Pape K, Bjornsgaard JH, Moster D, Bracken M, Romundstad P. Premature adult death in individuals born preterm : A sibling comparison in a prospective nationwide follow-up. PLoS One. 2016 Nov 7;11(11):e0165051.

Gunnes MW, Lie RT, Bjørge T, Syse A, Ruud E, Wesenberg F, Moster D. Suicide and violent deaths in survivors of cancer in childhood, adolescence and young adulthood- a national cohort study. International Journal of Cancer 2017 Feb 1;140(3):575-580.

Berg E, Haaland ØA, Feragen KB, Filip C, Vindenes HA, Moster D, Lie RT, Sivertsen Å. Health status among adults born with an oral cleft in Norway. JAMA Pediatrics 2016 Nov 1;170(11):1063-1070.

Berg E, Sivertsen Å, Ariansen AMS, Filip C, Vindenes HA, Feragen KJB, Moster D, Lie RT, Haaland ØA. Socio-economic status and reproduction among adults born with an oral cleft: A population-based cohort study in Norway. PLoS One. 2016 Sep 15;11(9): e0162196.

Forthun I, Wilcox AJ, Strandberg-Larsen K, Moster D, Nohr E, Lie RT, Surén P, Tollånes M. Maternal pre-pregnancy body mass index and risk of cerebral palsy in offspring. Pediatrics 2016 Oct;138(4).

Tollånes MC, Strandberg-Larsen K, Forthun I, Knudsen TM, Moster D, Nybo Andersen AM, Stoltenberg C, Olsen J, Wilcox AJ. Cohort profile: Cerebral Palsy in the Norwegian and Danish birth cohorts (MOBAND-CP). BMJ Open 2016 Sep 2;6(9):e012777.

Gunnes MW, Lie RT, Bjørge T, Syse A, Ruud E, Wesenberg F, Moster D. Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study. Cancer. 2016 Dec 15;122(24):3873-3882.

Tollånes MC, Strandberg-Larsen K, Eichelberger KY, Moster D, Lie RT, Brantsæter AL, Meltzer HM, Stoltenberg C, Wilcox AJ. Intake of caffeinated soft drinks before and during pregnancy, but not total caffeine intake, is associated with Increased Cerebral Palsy Risk in the Norwegian Mother and Child Cohort Study. J Nutr. 2016 Sep;146(9):1701-6.

Tollånes MC, Wilcox AJ, Stoltenberg C, Lie RT, Moster D. Neurodevelopmental Disorders or Early Death in Siblings of Children with Cerebral Palsy. Pediatrics. 2016 Aug;138(2).

Gunnes MW, Lie RT, Bjørge T, Ghaderi S, Ruud E, Syse A, Moster D. Reproduction and marriage among male survivors of cancer in childhood, adolescence and young adulthood - a national cohort study. Br J of Cancer. 2016 Feb 2;114(3):348-56.

Ghaderi S, Engeland A, Gunnes MW, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Educational attainment among long-term survivors of cancer in childhood and adolescence: a Norwegian population-based cohort study. J Cancer Surviv. 2016 Feb;10(1):87-95.

Kessler J, Moster D, Albrechtsen S. Intrapartum monitoring with cardiotocography and ST-waveform analysis in breech presentation: an observational study. BJOG. 2015 Mar;122(4):528-35.

Trønnes H, Wilcox AJ, Lie RT, Markestad T, Tollånes MC, Moster D. Associations of maternal atopic diseases with adverse pregnancy outcomes: a national cohort study. Paediatric and Perinatal Epidemiology. 2014 Nov;28(6):489-97.

Tollånes MC, Wilcox AJ, Lie RT, Moster D. Familial risk of cerebral palsy: population based cohort study. BMJ. 2014 Jul 15;349:g4294.

Jensen ET, Daniels JL, Stürmer T, Robinson WR, Williams CJ, Moster D, Juliusson PB, Vejrup K, Magnus P, Longnecker MP. Maternal hormonal contraceptive use and offspring overweight or obesity. Int J Obes (Lond). 2014 Oct;38(10):1275-81.

Trønnes H, Wilcox AJ, Lie RT, Markestad T, Moster D. Risk of cerebral palsy in relation to pregnancy disorders and preterm birth: a national cohort study. Dev Med Child Neurol. 2014 Aug;56(8):779-85.

Kessler J, Moster D, Albrechtsen S. Delay in intervention increases neonatal morbidity in births monitored with cardiotocography and ST-waveform analysis. Acta Obstet Gynecol Scand. 2014 Feb;93(2):175-81.

Trønnes H, Wilcox AJ, Lie RT, Markestad T, Moster D. The association of preterm birth with severe asthma and atopic dermatitis: a national cohort study. Pediatr Allergy Immunol. 2013 Dec;24(8):782-7.

Ghaderi S, Engeland A, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Increased uptake of social security benefits and occurrence of subsequent malignancies among long-term survivors of cancer in childhood, adolescence and young adulthood: A Norwegian population-based cohort study. British Journal of Cancer 2013; 108(7):1525-33.

Júlíusson PB, Roelants M, Nordal E, Furevik L, Eide GE, Moster D, Hauspie R, Bjerknes R. Growth references for 0-19 year-old Norwegian children for length/height, weight, body mass index and head circumference. Ann Hum Biol. 2013 May; 40(3): 220-7.

Eide MG, Moster D, Irgens LM, Reichborn-Kjennerud T, Stoltenberg C, Skjærven R, Susser E, Abel K. Degree of fetal growth restriction associated with schizophrenia risk in a national cohort. Psychol Med. 2013 Oct; 43(10): 2057-66.

Kessler J, Moster D, Albrechtsen S. Intrapartum monitoring of high-risk deliveries with ST analysis of the fetal electrocardiogram: an observational study of 6010 deliveries. Acta Obstet Gynecol Scand. 2013 Jan; 92(1): 75-84.

Ghaderi S, Lie RT, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Cancer in childhood, adolescence and young adults: A population-based study of changes in risk of cancer death during four decades in Norway. Cancer Causes Control. 2012 Aug; 23(8): 1297-305. Erratum in Cancer Causes Control. 2013 Oct 12.

Moster D, Wilcox AJ, Vollset SE, Markestad T, Lie RT. Cerebral palsy among term and post-term births. JAMA. 2010;304(9):976-82.

Tjora E, Karlsen L, Moster D, Markestad T. Early severe weight loss in newborns after discharge from regular nurseries. Acta Paediatr. 2010;99(5):654-7. Epub 2010 Jan 18.

Rosendahl K, Dezateux C, Fosse K, Aase H, Aukland S, Reigstad H, Alsaker T, Moster D, Lie RT, Markestad T. Immediate treatment versus sonographic surveillance for mild hip dysplasia in newborns. Pediatrics 2010;125(1):e9-16. Epub 2009 Dec 21.

Júlíusson PB, Roelants M, Eide GE, Moster D, Juul A, Hauspie R, Waaler PE, Bjerknes R. Vekstkurver for norske barn. Tidsskr Nor Legeforen 2009; 129:281-6.

Meberg A, Andreassen A, Brunvand L, Markestad T, Moster D, Nietsch L, Silberg IE, Skålevik JE. Pulse oximetry screening as a complementary strategy to detect critical congenital heart defects. Acta Paediatr. 2009; 98: 682-6. Epub 2008 Jan 15.

Moster D, Lie RT, Markestad T. Long-term medical and social consequences of preterm birth. N Engl J Med. 2008; 359: 262-73.

Tollånes MC, Moster D, Daltveit AK, Irgens LM. Cesarean section and risk of severe childhood asthma: a population-based cohort study. J Pediatr. 2008; 153: 112-6.